Optimization of antibiotic therapy by procalcitonin
نویسندگان
چکیده
منابع مشابه
Using Procalcitonin to Guide Antibiotic Therapy
Procalcitonin levels rise in response to systemic inflammation, especially of bacterial origin. Multiple randomized controlled trials have demonstrated that procalcitonin-based algorithms can safely reduce antibiotic use in 2 clinical scenarios. First, in stable, low-risk patients with respiratory infections, procalcitonin levels of <0.25 µg/L can guide the decision to withhold antibiotics or s...
متن کاملProcalcitonin-guided antibiotic therapy: a potentially effective and efficient strategy.
Antimicrobial resistance has emerged as a major issue affecting both patient outcomes and overall resources in healthcare systems. In addition, the evidence that antibiotic use causes resistance is increasingly recognized as a sound rationale to prevent their inappropriate prescription [1]. Respiratory tract infections contribute significantly to the problem of antibiotic misuse. Approximately ...
متن کاملProcalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy
BACKGROUND Sepsis is a global healthcare problem, characterized by whole body inflammation in response to microbial infection, which leads to organ dysfunction. It is becoming a frequent complication in hospitalized patients. Early and differential diagnosis of sepsis is needed critically to avoid unnecessary usage of antimicrobial agents and for proper antibiotic treatments through the screeni...
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Procalcitonin – Assisted Antibiotic Strategy in Sepsis
Sepsis is one of the biggest challenges in critical care nowadays. Defining sepsis is a difficult task on its own and its diagnosis and treatment requires well trained, devoted personnel with interdisciplinary collaboration in order to provide the patients the best chance for survival. Immediate resuscitation, early adequate antimicrobial therapy, source control and highly sophisticated organ s...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2009
ISSN: 1364-8535
DOI: 10.1186/cc7551